Bus from Mexico City to Guadalajara
ETN Turistar Lujo + Primera Plus Diamante · ~7 hours overnight · $35–$65 USD · Multiple daily including overnight cama
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The Mexico City → Guadalajara route is the standard overland transit between Mexico's two largest cities — most travelers either take the overnight cama Pullman to sleep through, or fly direct (~1.5 h, $40–$130 USD on Aeroméxico, Volaris, VivaAerobus).
Spring Bus connects you to operators running this route — ETN Turistar Lujo (cama class, fully reclining seats, A/C, onboard service) + Primera Plus Diamante (executive class). Multiple daily including overnight departures (9-11 PM). Buses leave from CDMX Terminal del Norte; arrive at Guadalajara's Nueva Central Camionera ~10 km southeast of downtown.
Route details: Mexico City to Guadalajara
Travel time
7 h
Distance
540 km
Typical fare
$35 – $65 USD per person
Frequency
Multiple daily including overnight cama
First departure
Approx. 7:00 AM
Last departure
Approx. 11:00 PM (overnight)
Operators on this route
ETN Turistar Lujo · Primera Plus Diamante · Futura
Pickup at Mexico City
Terminal del Norte (Metro Autobuses del Norte, line 5)
Drop-off at Guadalajara
Nueva Central Camionera (~10 km southeast of Centro Histórico, ~$5–$8 USD taxi to downtown)
About the journey
The Mexico City → Guadalajara route is the standard transit between Mexico's two largest cities — ~7-hour Pullman trip on Highway 15D + 80D. The overnight cama service is the popular pick: depart Terminal del Norte ~9–11 PM, arrive Guadalajara Nueva Central Camionera ~4–6 AM. ETN Turistar Lujo + Primera Plus Diamante are the cama-class options with fully reclining seats.
Travel tips for Mexico City → Guadalajara
- Overnight cama ETN Turistar Lujo is the comfort pick — fully reclining seats, A/C, snack service. Depart CDMX ~9–11 PM, arrive Guadalajara ~4–6 AM.
- Flying is ~1.5 hours, $40–$130 USD — most travelers fly between these two cities. Bus is for budget or those who specifically want the overnight experience.
- Terminal del Norte in CDMX — Metro line 5, taxi from central neighborhoods ~$8–$12 USD.
- Nueva Central Camionera in Guadalajara has 7 modules organized by operator — check your ticket for which module + Uber from there to Centro/Providencia ~$5–$8 USD.
- Pre-book in high season (December–April, Día de los Muertos, Easter) — overnight cama fills up.
- Bring an eye mask + neck pillow for the overnight ride.
Frequently asked questions
How long is the bus from Mexico City to Guadalajara?
**About 7 hours** on ETN or Primera Plus Pullman — direct overnight cama service. Day buses also run ~7 hours.
How much is the overnight cama bus from CDMX to Guadalajara?
**$35 – $65 USD per person** depending on class — Primera Plus Diamante $35–$50, ETN Turistar Lujo cama-class $45–$65. Includes fully reclining seats, A/C, onboard snacks.
Should I take the overnight bus or fly to Guadalajara?
**Overnight cama** ($35–$65 USD, 7 hours, sleep through, save a hotel night) for budget + experience. **Flight** ($40–$130 USD, 1.5 hours on Aeroméxico, Volaris, VivaAerobus) if you're prioritizing time. Most travelers fly; bus is the budget/atmospheric option.
Where do I catch the bus from CDMX to Guadalajara?
**Terminal del Norte (Central de Autobuses del Norte)** in northern CDMX — Metro Autobuses del Norte (line 5). Taxi from central CDMX neighborhoods ~$8–$12 USD. NOT TAPO (which is for southeast routes).
Where does the bus drop me in Guadalajara?
**Nueva Central Camionera** ~10 km southeast of downtown — organized into 7 modules by operator. Uber/taxi to **Centro Histórico** or **Providencia/Lafayette** ~$5–$8 USD, ~15–20 min.
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